Wednesday, January 30, 2019

Is Interstitial Cystitis an Autoimmune Disease?

What is an autoimmune disease?

An autoimmune disorder occurs when the body's immune system attacks and destroys healthy body tissue by mistake. Autoimmune disorder causes abnormally low activity or overactivity of the immune system. In cases of the immune system overactivity, the body attacks and damages its own tissues. Immune deficiency diseases decrease the body's ability to fight invaders, causing vulnerability to infections. In response to an unknown trigger, the immune system may begin producing antibodies that instead of fighting infections, attack the body's own tissues.

How many auto-immune diseases are there?

There are almost 100 autoimmune diseases.

What is the treatment for auto-immune diseases?

Treatment for autoimmune diseases generally focuses on reducing immune system activity.

Is Interstitial Cystitis an auto-immune disease?

Yes, Interstitial Cystitis is one of the auto-immune diseases.

Are all auto-immune diseases rare?

Many auto-immune disorders like Type 1 Diabetes, Ankylosing spondylitis, and Chagas diseases are common however diseases like adult Still's disease, interstitial cystitis, and achalasia are rare.

Are all auto-immune diseases chronic and progressive?

Some autoimmune diseases like auto-immune hepatitis, Lyme disease are chronic, some are progressive like MMN, MS while others like herpes gestationis are temporary.

Here is the list of auto-immune diseases includes:

·         Achalasia (rare)
·         Addison’s disease(rare)
·         Adult Still's disease(rare)
·         Agammaglobulinemia
·         Alopecia areata
·         Amyloidosis
·         Ankylosing spondylitis (common and hereditary)
·         Anti-GBM/Anti-TBM nephritis(rare)
·         Antiphospholipid syndrome
·         Autoimmune angioedema
·         Autoimmune dysautonomia
·         Autoimmune encephalomyelitis
·         Autoimmune hepatitis
·         Autoimmune inner ear disease (AIED) (rare)
·         Autoimmune myocarditis
·         Autoimmune oophoritis
·         Autoimmune orchitis
·         Autoimmune pancreatitis
·         Autoimmune retinopathy
·         Autoimmune urticaria
·         Baló disease(rare)
·         Behcet’s disease
·         Benign mucosal pemphigoid(rare)
·         Bullous pemphigoid
·         Castleman disease (CD) (rare)
·         Celiac disease
·         Chagas disease (common)
·         Chronic recurrent multifocal osteomyelitis (CRMO) (rare) 1::1000000
·         Cicatricial pemphigoid(rare)
·         Cogan’s syndrome
·         Cold agglutinin disease
·         Congenital heart block(rare)
·         Coxsackie myocarditis
·         CREST syndrome
·         Crohn’s disease
·         Dermatitis herpetiformis
·         Dermatomyositis
·         Discoid lupus
·         Dressler’s syndrome
·         Endometriosis
·         Eosinophilic esophagitis (EoE)
·         Eosinophilic fasciitis(rare)
·         Erythema nodosum
·         Evans syndrome(rare)
·         Fibromyalgia(not autoimmune but accompany other autoimmune diseases)
·         Fibrosing alveolitis
·         Giant cell myocarditis(rare)
·         Glomerulonephritis
·         Goodpasture’s syndrome
·         Granulomatosis with Polyangiitis(rare)
·         Graves’ disease
·         Guillain-Barre syndrome(rare)
·         Hashimoto’s thyroiditis
·         Hemolytic anemia
·         Henoch-Schonlein purpura (HSP)
·         Hypogammalglobulinemia
·         IgA Nephropathy
·         Inclusion body myositis (IBM)
·         Interstitial cystitis (IC)
·         Juvenile arthritis
·         Juvenile myositis (JM)
·         Kawasaki disease
·         Lambert-Eaton syndrome
·         Leukocytoclastic vasculitis
·         Lichen planus
·         Lichen sclerosus
·         Ligneous conjunctivitis(rare)
·         Linear IgA disease (LAD)
·         Lupus
·         Lyme disease chronic
·         Meniere’s disease
·         Microscopic polyangiitis (MPA)
·         Mixed connective tissue disease (MCTD) (rare)
·         Mooren’s ulcer(rare)
·         Mucha-Habermann disease
·         Multiple sclerosis
·         Myasthenia gravis
·         Myositis
·         Narcolepsy
·         Neonatal Lupus
·         Neuromyelitis optica
·         Neutropenia
·         Ocular cicatricial pemphigoid(rare)
·         Optic neuritis
·         Palindromic rheumatism (PR)
·         PANDAS(rare)
·         Parry Romberg syndrome(rare)
·         Parsonage-Turner syndrome
·         Pemphigus
·         Peripheral neuropathy
·         Perivenous encephalomyelitis
·         Pernicious anemia (PA)
·         POEMS syndrome(rare)
·         Polyarteritis nodosa
·         Polymyalgia rheumatica
·         Polymyositis(rare)
·         Postpericardiotomy syndrome
·         Primary biliary cirrhosis
·         Primary sclerosing cholangitis
·         Progesterone dermatitis(rare)
·         Psoriasis
·         Psoriatic arthritis
·         Pure red cell aplasia (PRCA) (rare)
·         Pyoderma gangrenosum(rare)
·         Raynaud’s phenomenon
·         Reactive Arthritis
·         Reflex sympathetic dystrophy
·         Relapsing polychondritis(rare)
·         Restless legs syndrome (RLS)
·         Retroperitoneal fibrosis(rare)
·         Rheumatic fever
·         Rheumatoid arthritis
·         Sarcoidosis
·         Schmidt syndrome(rare)
·         Scleritis
·         Scleroderma
·         Sjögren’s syndrome
·         Stiff person syndrome (SPS) (rare)
·         Susac’s syndrome(rare)
·         Sympathetic ophthalmia (SO)
·         Takayasu’s arteritis
·         Thrombocytopenic purpura (TTP)
·         Tolosa-Hunt syndrome (THS) (rare)
·         Transverse myelitis
·         Type 1 diabetes
·         Ulcerative colitis (UC)
·         Uveitis
·         Vasculitis
·         Vitiligo
·         Vogt-Koyanagi-Harada Disease(rare)

List courtesy:


  1. Thank you for this information, Balaka! I had been wanting to read it since quite some time, but kept forgetting.

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ESSIC 2019- Amsterdam

Excerpts from the minutes of the meeting (MOM) of the annual ESSIC meeting of 2019. Thanks to International Painful Bladder Foundation for...